BDBM674422 N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano[3,2-b]pyridin-4-yl]methanamine dihydrochloride::US20240150370, Example 5::US20240150370, Example 7

SMILES CNC[C@@H]1C[C@@H](C)Oc2cccnc12

InChI Key InChIKey=NXRRJKFNWSQVHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674422   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674422(N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM674422(N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent