BDBM674384 US20240150335, Compound 12

SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@@H]1CNCCCO1)C#N)-c1ccc2cnn(C3CCOCC3)c2c1

InChI Key InChIKey=DBKAJGGNUTXWPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674384   

TargetDipeptidyl peptidase 1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM674384(US20240150335, Compound 12)
Affinity DataIC50: 2.38nMAssay Description:Experimental Methods:1× activation buffer: 5 mM DTT 0.01% (V/V) Triton X-100 (preparation for current use);1× assay buffer: 50 mM NaCl 5 mM DTT 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM674384(US20240150335, Compound 12)
Affinity DataIC50: 1.81nMAssay Description:Experimental Methods:1× activation buffer: 5 mM DTT 0.01% (V/V) Triton X-100 (preparation for current use);1× assay buffer: 50 mM NaCl 5 mM DTT 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent