BDBM674291 3,5-difluoro-4- hydroxy-N-({4-[3-(6- methylpyridazin-3-yl)- 1,2,4-oxadiazol-5- yl]bicyclo[2.2.2]octan- 1-yl}methyl)benzamide::US20240150334, Example 123

SMILES Cc1ccc(nn1)-c1noc(n1)[C@]12CC[C@](CNC(=O)c3cc(F)c(O)c(F)c3)(CC1)CC2

InChI Key InChIKey=AAGITNRDJGADPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674291   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674291(3,5-difluoro-4- hydroxy-N-({4-[3-(6- methylpyridaz...)
Affinity DataIC50: 10nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
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