BDBM674272 3,5-difluoro-4- hydroxy-N-({(1r,4r)- 4-[6-(imidazo[1,2-a] pyridin-2-yl)-2H- indazol-2-yl] cyclohexyl}methyl) benzamide, trifluoroacetate salt::US20240150334, Example 103

SMILES Oc1c(F)cc(cc1F)C(=O)NC[C@H]1CC[C@@H](CC1)n1cc2ccc(cc2n1)-c1cn2ccccc2n1

InChI Key InChIKey=HPBOJRDKBQFQEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674272   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674272(3,5-difluoro-4- hydroxy-N-({(1r,4r)- 4-[6-(imidazo...)
Affinity DataIC50: 7.90nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent