BDBM674267 3,5-difluoro-4- hydroxy-N- ({(1r,4r)-4-[6-(7H- pyrrolo[2,3-d] pyrimidin-2-yl)-2H- indazol-2-yl] cyclohexyl}methyl) benzamide::US20240150334, Example 97

SMILES Oc1c(F)cc(cc1F)C(=O)NC[C@H]1CC[C@@H](CC1)n1cc2ccc(cc2n1)-c1ncc2cc[nH]c2n1

InChI Key InChIKey=CKCFCYUPAIRAKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674267   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674267(3,5-difluoro-4- hydroxy-N- ({(1r,4r)-4-[6-(7H- pyr...)
Affinity DataIC50: 8.20nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
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