BDBM674219 3,5-difluoro-4- hydroxy-N- {[(1r,4r)-4-{6-[1- methyl-3-(trifluoro- methyl)-1H-pyrazol- 4-yl]-2H-indazol-2- yl}cyclohexyl] methyl}benzamide::US20240150334, Example 49

SMILES Cn1cc(c(n1)C(F)(F)F)-c1ccc2cn(nc2c1)[C@H]1CC[C@H](CNC(=O)c2cc(F)c(O)c(F)c2)CC1

InChI Key InChIKey=DFOVFSDLJULDBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674219   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674219(3,5-difluoro-4- hydroxy-N- {[(1r,4r)-4-{6-[1- meth...)
Affinity DataIC50: 26nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674219(3,5-difluoro-4- hydroxy-N- {[(1r,4r)-4-{6-[1- meth...)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed