BDBM674214 N-{[(1r,4r)-4-{6-[1- (difluoromethyl)-1H- pyrazol-4-yl]-2H- indazol-2-yl} cyclohexyl]methyl}- 3,5-difluoro-4- hydroxybenzamide::US20240150334, Example 44

SMILES Oc1c(F)cc(cc1F)C(=O)NC[C@H]1CC[C@@H](CC1)n1cc2ccc(cc2n1)-c1cnn(c1)C(F)F

InChI Key InChIKey=BWIASFCXGPXAFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674214   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674214(N-{[(1r,4r)-4-{6-[1- (difluoromethyl)-1H- pyrazol-...)
Affinity DataIC50: 15nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674214(N-{[(1r,4r)-4-{6-[1- (difluoromethyl)-1H- pyrazol-...)
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed