BDBM674202 N-({(1r,4r)-4-[5- (cyclopropyl-methoxy)-2H- pyrazolo[3,4-c]pyridin-2-yl] cyclohexyl}methyl)- 3,5-difluoro-4- hydroxybenzamide, ammonium salt::US20240150334, Example 32

SMILES Oc1c(F)cc(cc1F)C(=O)NC[C@H]1CC[C@@H](CC1)n1cc2cc(OCC3CC3)ncc2n1

InChI Key InChIKey=UQAHZVXJVMWXGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674202   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674202(N-({(1r,4r)-4-[5- (cyclopropyl-methoxy)-2H- pyrazo...)
Affinity DataIC50: 4.30nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
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