BDBM674196 N-{[(1r,4r)-4-(6- chloro-2H- indazol-2- yl)cylohexyl]methyl}- 2,3,5-trifluoro-4- hydroxybenzamide::US20240150334, Example 25

SMILES Oc1c(F)cc(C(=O)NC[C@H]2CC[C@@H](CC2)n2cc3ccc(Cl)cc3n2)c(F)c1F

InChI Key InChIKey=VIWCQDMYRZNNBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674196   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674196(N-{[(1r,4r)-4-(6- chloro-2H- indazol-2- yl)cylohex...)
Affinity DataIC50: 4.30nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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