BDBM674177 2,3,5-trifluoro-4-hydroxy-N- [(4-{3-[5-(trifluoromethyl) pyrimidin-2-yl]-1,2,4- oxadiazol-5-yl}bicyclo[2.2.2] octan-1-yl)methyl]benzamide::US20240150334, Example 3

SMILES Oc1c(F)cc(C(=O)NC[C@@]23CC[C@](CC2)(CC3)c2nc(no2)-c2ncc(cn2)C(F)(F)F)c(F)c1F

InChI Key InChIKey=GDRXKBRHPMGANI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674177   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674177(2,3,5-trifluoro-4-hydroxy-N- [(4-{3-[5-(trifluorom...)
Affinity DataIC50: 5.5nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
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