BDBM673772 US20240150300, Compound I-4

SMILES COc1cccc(c1)-c1ccc(=O)n(n1)[C@@H](C)c1ccc(cc1)C(=O)Nc1ccccc1N

InChI Key InChIKey=KEFZMSOQKVVPLR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 673772   

TargetHistone deacetylase 1(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM673772(US20240150300, Compound I-4)
Affinity DataIC50: 35.2nMAssay Description:Human recombinant HDAC family proteins with His and GST tags were expressed using insect baculovirus expression system, and a biologically active HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM673772(US20240150300, Compound I-4)
Affinity DataIC50: 1.00E+4nMAssay Description:Human recombinant HDAC family proteins with His and GST tags were expressed using insect baculovirus expression system, and a biologically active HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent