BDBM673770 US20240150300, Compound I-3

SMILES C[C@@H](c1ccc(cc1)C(=O)Nc1ccccc1N)n1nc(ccc1=O)-c1cccc(Cl)c1

InChI Key InChIKey=RJORPXFSDUVPBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 673770   

TargetHistone deacetylase 1(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM673770(US20240150300, Compound I-3)
Affinity DataIC50: 52.4nMAssay Description:Human recombinant HDAC family proteins with His and GST tags were expressed using insect baculovirus expression system, and a biologically active HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM673770(US20240150300, Compound I-3)
Affinity DataIC50: 1.00E+4nMAssay Description:Human recombinant HDAC family proteins with His and GST tags were expressed using insect baculovirus expression system, and a biologically active HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent