BDBM673729 (1r,4S,7′S)-4-(3-chloroanilino)-7′-[(2R)-3-{[(5R,8R)-5,8-dimethyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}-2-methylpropyl]-2′,3′,7′,8′-tetrahydrospiro[cyclohexane-1,6′-indeno[5,6-b][1,4]dioxine]-4-carboxylic acid::US20240150293, Example 963

SMILES C[C@@H](COc1ccnc2[C@H](C)CC[C@@H](C)c12)C[C@H]1Cc2cc3OCCOc3cc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O

InChI Key InChIKey=PWAFQDFYMDZNBC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673729   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673729(US20240150293, Example 963 | (1r,4S,7′S)-4-(...)
Affinity DataKi:  0.0240nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent