BDBM6717 1,4,14,24-tetraazaheptacyclo[16.10.1.0^{2,17}.0^{3,11}.0^{5,10}.0^{12,16}.0^{22,29}]nonacosa-2(17),3(11),5(10),6,8,12(16),18(29),19,21-nonaene-13,15-dione hydrochloride::aza-1,7-annulated indole deriv. 28

SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1n3CCCCNCc4cccc(c34)c21

InChI Key InChIKey=HCHFQFVBCUYUIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6717   

LigandPNGBDBM6717(1,4,14,24-tetraazaheptacyclo[16.10.1.0^{2,17}.0^{3...)
Affinity DataIC50: 84nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2005
Entry Details Article
PubMed
LigandPNGBDBM6717(1,4,14,24-tetraazaheptacyclo[16.10.1.0^{2,17}.0^{3...)
Affinity DataIC50: 200nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2005
Entry Details Article
PubMed
LigandPNGBDBM6717(1,4,14,24-tetraazaheptacyclo[16.10.1.0^{2,17}.0^{3...)
Affinity DataIC50: 40nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2005
Entry Details Article
PubMed