BDBM670937 US20240140975, Compound A212::US20240140975, Compound A213::US20240140975, Compound A214

SMILES CC(C)[C@H](N)C(=O)O[C@@H]1[C@@H](CO)O[C@](C#N)([C@@H]1O)c1ccc2c(N)ncnn12

InChI Key InChIKey=HKSWBJIPMIGHBT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 670937   

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM670937(US20240140975, Compound A214 | US20240140975, Comp...)
Affinity DataEC50:  110nMAssay Description:Determining the inhibitory activity of compounds of the present invention on the replication of 2019 novel coronavirus (SARS-CoV-2): Vero E6 cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM670937(US20240140975, Compound A214 | US20240140975, Comp...)
Affinity DataEC50:  100nMAssay Description:Determining the inhibitory activity of compounds of the present invention on the replication of 2019 novel coronavirus (SARS-CoV-2): Vero E6 cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM670937(US20240140975, Compound A214 | US20240140975, Comp...)
Affinity DataEC50:  110nMAssay Description:Determining the inhibitory activity of compounds of the present invention on the replication of 2019 novel coronavirus (SARS-CoV-2): Vero E6 cells we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent