BDBM670922 US20240140962, Compound 6

SMILES CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2ncc3CCc4c(sc(CCO)c4-c3n2)C(N)=O)c1

InChI Key InChIKey=QYBMNLBGLNBFDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670922   

TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670922(US20240140962, Compound 6)
Affinity DataIC50: 6.90nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent