BDBM670917 US20240140962, Compound 1

SMILES CSc1sc(C(N)=O)c2CCc3cnc(Nc4cc(ccc4OC(F)(F)F)N4CCN(C)CC4)nc3-c12

InChI Key InChIKey=VGKJUXZAFATSHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670917   

TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670917(US20240140962, Compound 1)
Affinity DataIC50: 4.40nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent