BDBM670833 (R)-3-(5-ethoxy-2-fluorophenyl)-1- isopropyl-N-(4-methyl-1,1- dioxidotetrahydro-2H-thiopyran-4- yl)-4,5,6,7-tetrahydro-1H-indazole- 6-carboxamide::US20240140938, Example 54

SMILES CCOc1ccc(F)c(c1)-c1nn(C(C)C)c2C[C@@H](CCc12)C(=O)NC1(C)CCS(=O)(=O)CC1

InChI Key InChIKey=UDXCFEGGQNJJIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670833   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670833(US20240140938, Example 54 | (R)-3-(5-ethoxy-2-fluo...)
Affinity DataIC50: 1.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent