BDBM670768 N-[(3R,4R)-4-[2-(4-cyanophenoxy)phenyl]-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-3-piperidyl]acetamide::US20240140933, Example 58

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CC[C@@H]([C@H](C1)NC(C)=O)c1ccccc1Oc1ccc(cc1)C#N

InChI Key InChIKey=JDQKURKYFAXJNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670768   

LigandPNGBDBM670768(N-[(3R,4R)-4-[2-(4-cyanophenoxy)phenyl]-1-[7-(ethy...)
Affinity DataIC50: 55nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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