BDBM670764 1-cyano-N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-4-phenyl-3-piperidyl]azetidine-3-carboxamide::US20240140933, Example 54

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CC[C@@H]([C@H](C1)NC(=O)C1CN(C1)C#N)c1ccccc1

InChI Key InChIKey=JWALGNPYXYMEQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670764   

LigandPNGBDBM670764(1-cyano-N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-me...)
Affinity DataIC50: 18nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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