BDBM670763 N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-4-phenyl-3-piperidyl]ethenesulfonamide::US20240140933, Example 53

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CC[C@@H]([C@H](C1)NS(=O)(=O)C=C)c1ccccc1

InChI Key InChIKey=DTNJUHMKUOMZQI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670763   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Hoffmann-La Roche

US Patent

LigandBDBM670763(N-[(3R,4R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-o...)Copy SMILESCopy InChI

Affinity DataIC50: 32nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2024
Entry Details
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