BDBM670684 US20240140931, Compound 261

SMILES CCNC(=O)C#Cc1ccc2CC3(CCN(CC3)c3ncc(Sc4ccnc(N)n4)nc3C)[C@H](N)c2c1

InChI Key InChIKey=IUGRNXNVMYPWFP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670684   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Hutchmed

US Patent

LigandBDBM670684(US20240140931, Compound 261)Copy SMILESCopy InChI

Affinity DataIC50: 0.900nMAssay Description:1. Reagents and MaterialsHuman full-length SHP2 recombinant protein: BPS Bioscience, Cat #79018;SHP2 substrate DiFMUP (1 mM): BPS Bioscience, Cat #79...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2024
Entry Details
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