BDBM670578 (S)-1-(3-(1-amino-1′-(6-amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-1,3-dihydrospiro[indene-2,4′-piperidin]-6-yl)prop-2-yn-1-yl)urea::US20240140931, Compound 159
SMILES COc1ccc(CN(CC#Cc2ccc3CC4(CCN(CC4)c4cnc(Sc5ccnc(N)c5Cl)c(N)n4)[C@H](N[S@](=O)C(C)(C)C)c3c2)C#N)cc1
InChI Key InChIKey=SAPMROBXSGSJSA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 670578
Affinity DataIC50: 1nMAssay Description:1. Reagents and MaterialsHuman full-length SHP2 recombinant protein: BPS Bioscience, Cat #79018;SHP2 substrate DiFMUP (1 mM): BPS Bioscience, Cat #79...More data for this Ligand-Target Pair