BDBM670509 (S)-(3-(1-amino-6-(3-methoxyprop-1-yn-1-yl)-1,3-dihydrospiro[indene-2,4′-piperidin]-1′-yl)-6-((2-aminopyrimidin-4-yl)thio)pyrazin-2-yl)methanol::US20240140931, Compound 87

SMILES COCC#Cc1ccc2CC3(CCN(CC3)c3ncc(Sc4ccnc(N)n4)nc3CO)[C@H](N)c2c1

InChI Key InChIKey=HGOVDKKJKAZYAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670509   

LigandPNGBDBM670509((S)-(3-(1-amino-6-(3-methoxyprop-1-yn-1-yl)-1,3-di...)
Affinity DataIC50: 1nMAssay Description:1. Reagents and MaterialsHuman full-length SHP2 recombinant protein: BPS Bioscience, Cat #79018;SHP2 substrate DiFMUP (1 mM): BPS Bioscience, Cat #79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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