BDBM670473 US20240140931, Compound 78::US20240140931, Compound 88

SMILES COc1c(F)ccc(c1F)-n1c(C)nc(cc1=O)N1CCC2(Cc3ccc(cc3[C@H]2N)C#C)CC1

InChI Key InChIKey=WDLKJTWJGNCGOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 670473   

LigandPNGBDBM670473(US20240140931, Compound 88 | US20240140931, Compou...)
Affinity DataIC50: 3nMAssay Description:1. Reagents and MaterialsHuman full-length SHP2 recombinant protein: BPS Bioscience, Cat #79018;SHP2 substrate DiFMUP (1 mM): BPS Bioscience, Cat #79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent

LigandPNGBDBM670473(US20240140931, Compound 88 | US20240140931, Compou...)
Affinity DataIC50: 0.800nMAssay Description:1. Reagents and MaterialsHuman full-length SHP2 recombinant protein: BPS Bioscience, Cat #79018;SHP2 substrate DiFMUP (1 mM): BPS Bioscience, Cat #79...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent