BDBM669925 US20240132525, Example 001
SMILES Cc1cnc(Nc2ccc3B(O)OCc3c2)nc1NC1CCCC1C#N
InChI Key InChIKey=GQLDUOUBEAJSNB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 669925
Affinity DataIC50: 1.10nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
Affinity DataIC50: 24.7nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Boehringer Ingelheim Animal Health Usa
US Patent
Boehringer Ingelheim Animal Health Usa
US Patent
Affinity DataIC50: 362nMAssay Description:Reagent: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij 35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO, where r...More data for this Ligand-Target Pair