BDBM669890 (S, 13E, 14E)-12-amino-2-ethyl-45-fluoro-6-methyl-9-oxo-5,8-dioxa-2-aza-1(5,3)-pyrazolo[1,5-a]pyrimidine-4(1,2)-benzocyclononane-46 carbonitrile::US20240132517, Example 2

SMILES CCN1Cc2c(O[C@@H](C)COC(=O)c3c(N)nn4ccc1nc34)ccc(F)c2C#N

InChI Key InChIKey=QCSPHKYKAODHGS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 669890   

TargetHepatocyte growth factor receptor(Human)
Goharmony Therapeutics (Shenzhen) Co.

US Patent
LigandPNGBDBM669890(US20240132517, Example 2 | (S, 13E, 14E)-12-amino-...)
Affinity DataIC50: 1.80nMAssay Description:The operation method is briefly described as follows:The powders of the compound were dissolved in 100% DMSO to make a 10 mM stock solution. The init...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
Goharmony Therapeutics (Shenzhen) Co.

US Patent
LigandPNGBDBM669890(US20240132517, Example 2 | (S, 13E, 14E)-12-amino-...)
Affinity DataIC50: 30nMAssay Description:The operation method is briefly described as follows:The powders of the compound were dissolved in 100% DMSO to make a 10 mM stock solution. The init...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
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TargetMacrophage colony-stimulating factor 1 receptor(Human)
Goharmony Therapeutics (Shenzhen) Co.

US Patent
LigandPNGBDBM669890(US20240132517, Example 2 | (S, 13E, 14E)-12-amino-...)
Affinity DataIC50: 2.20nMAssay Description:The operation method is briefly described as follows:The powders of the compound were dissolved in 100% DMSO to make a 10 mM stock solution. The init...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
Go to US Patent