BDBM669828 4-(6-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-N—((S)-piperidin-3-yl)-5-(trifluoromethyl)pyrimidine-2-amine ::US20240132489, Compound 2
SMILES C[C@@H]1CN([C@H](C)CO1)c1ccc2c(c[nH]c2n1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F
InChI Key InChIKey=FNGPJZKKKOUHFY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 669828
Affinity DataIC50: 10.4nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
Affinity DataIC50: 4.38E+3nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+3nMAssay Description:The test was performed in a U-shaped bottom 384-well plate (coming, 4512 #), and the reaction temperature was 27° C. CDK7/CyclinH was diluted in a te...More data for this Ligand-Target Pair