BDBM669507 US11964990, Example 50

SMILES CC1(C)C[C@H]2OCCCOC[C@@H]3CN(CCN3CC2=C(C1)c1ccc(Cl)cc1)c1ccc(C(=O)NS(=O)(=O)c2cnc(OC[C@H]3CC[C@@](C)(O)CC3)c(Cl)c2)c(c1)N1CCCOc2nc3[nH]ccc3cc12

InChI Key InChIKey=SCJDJOHDDONUKF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669507   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669507(US11964990, Example 50)
Affinity DataKi:  0.237nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
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TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669507(US11964990, Example 50)
Affinity DataKi:  39.7nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent