BDBM669505 US11964990, Example 47::US20250066388, Example 47

SMILES COC[C@@]%10(F)C[C@@H](CNc9ccc(S(=O)(=O)NC(=O)c5ccc(N4CCN3CC2=C(c1ccc(Cl)cc1)CC(C)(C)C[C@H]2OCCCOC[C@@H]3C4)cc5N8CCCOc7nc6[nH]ccc6cc78)cc9[N+](=O)[O-])C%10

InChI Key InChIKey=UBKXEYWYQZYHNE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 669505   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669505(US11964990, Example 47 | US20250066388, Example 47)
Affinity DataKi:  0.280nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669505(US11964990, Example 47 | US20250066388, Example 47)
Affinity DataKi:  0.280nMAssay Description:The samples were then mixed on a shaker for 1 minute and equilibrated for an additional 3 hours at room temperature. For each assay plate, a probe/an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669505(US11964990, Example 47 | US20250066388, Example 47)
Affinity DataKi:  25.8nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669505(US11964990, Example 47 | US20250066388, Example 47)
Affinity DataKi:  25.8nMAssay Description:The samples were then mixed on a shaker for 1 minute and equilibrated for an additional 3 hours at room temperature. For each assay plate, a probe/an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent