BDBM669495 US11964990, Example 37::US20250066388, Example 37

SMILES CC%11(C)CC(c1ccc(Cl)cc1)=C%10CN9CCN(c8ccc(C(=O)NS(=O)(=O)c4ccc(NC[C@H]3CC[C@H](N2CCOCC2)CO3)c([N+](=O)[O-])c4)c(N7CCCOc6nc5[nH]ccc5cc67)c8)C[C@H]9COCCCO[C@@H]%10C%11

InChI Key InChIKey=YPXKZLAOAZGOQT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 669495   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669495(US11964990, Example 37 | US20250066388, Example 37)
Affinity DataKi:  0.109nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669495(US11964990, Example 37 | US20250066388, Example 37)
Affinity DataKi:  0.109nMAssay Description:The samples were then mixed on a shaker for 1 minute and equilibrated for an additional 3 hours at room temperature. For each assay plate, a probe/an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669495(US11964990, Example 37 | US20250066388, Example 37)
Affinity DataKi:  4.61nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669495(US11964990, Example 37 | US20250066388, Example 37)
Affinity DataKi:  4.61nMAssay Description:The samples were then mixed on a shaker for 1 minute and equilibrated for an additional 3 hours at room temperature. For each assay plate, a probe/an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent