BDBM669478 US11964990, Example 20

SMILES C[C@@H]%10CO[C@@H](COc9ccc(S(=O)(=O)NC(=O)c5ccc(N4CCN3CC2=C(c1ccc(Cl)cc1)CC(C)(C)C[C@H]2OCCCOC[C@@H]3C4)cc5N8CCCOc7nc6[nH]ccc6cc78)cc9[N+](=O)[O-])CO%10

InChI Key InChIKey=PEXYZXNOHQLYNL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669478   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669478(US11964990, Example 20)
Affinity DataKi:  0.977nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669478(US11964990, Example 20)
Affinity DataKi:  17.3nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent