BDBM669473 US11964990, Example 15

SMILES CC%11(C)CC(c1ccc(Cl)cc1)=C%10CN9CCN(c8ccc(C(=O)NS(=O)(=O)c4ccc(NC[C@@H]3C[C@@](O)(C2CCC2)C3)c([N+](=O)[O-])c4)c(N7CCCOc6nc5[nH]ccc5cc67)c8)C[C@H]9COCCCO[C@@H]%10C%11

InChI Key InChIKey=NYPIQGDOTHUOSQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669473   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669473(US11964990, Example 15)
Affinity DataKi:  0.552nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669473(US11964990, Example 15)
Affinity DataKi:  13.9nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent