BDBM669460 US11964990, Example 2

SMILES CC%10(C)CC(c1ccc(Cl)cc1)=C9CN8CCN(c7ccc(C(=O)NS(=O)(=O)c3ccc(NC[C@H]2CC[C@](C)(O)CO2)c([N+](=O)[O-])c3)c(N6CCCOc5nc4[nH]ccc4cc56)c7)C[C@H]8COCCCO[C@@H]9C%10

InChI Key InChIKey=WHMDORUXYFGJLH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 669460   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM669460(US11964990, Example 2)
Affinity DataKi:  0.0490nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM669460(US11964990, Example 2)
Affinity DataKi:  9.30nMAssay Description:[Bcl-2 protein or Bcl-xL protein], [Probe], [Antibody],Protein Probe nM nM Antibody nMGST- F-Bak 1 100 Tb-anti- 1Bcl- Acetyl-(SEQ GST 2 ID NO: 3)-NH2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent