BDBM669352 US11964973, Example 347::US11964973, Example 348

SMILES CCO[C@H]1CN(CC[C@@H]1Oc1ccc(OC(C)C)cc1)c1cc(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=IKELHOYTFNLPQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 669352   

TargetDiacylglycerol kinase alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM669352(US11964973, Example 347 | US11964973, Example 348)
Affinity DataIC50: 44nMAssay Description:The DGKα and DGKζ reactions were performed using extruded liposomes (DGKα and DGKζ LIPGLO assays). The reactions were carried out...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM669352(US11964973, Example 347 | US11964973, Example 348)
Affinity DataIC50: 120nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays). The reactions were carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM669352(US11964973, Example 347 | US11964973, Example 348)
Affinity DataIC50: 3.60E+4nMAssay Description:The DGKα and DGKζ reactions were performed using either extruded liposome (DGKα and DGKζ LIPGLO assays). The reactions were carri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
Go to US Patent