BDBM668457 US20240124479, Compound 41-P2

SMILES C[C@@H](Nc1ncc(cn1)C(=O)N1CC[C@@H](C1)N(C)C(C)=O)c1ccc(cc1F)C(F)(F)F

InChI Key InChIKey=DSIQIIPHSFLSGV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 668457   

TargetPantetheinase(Human)
Shanghai Meiyue Biotech Development Co.

US Patent
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 0.300nMAssay Description:A certain mass of the compound was weighed precisely, and prepared with DMSO and reaction buffer (50 mM Tris base, 50 mM KCl, 1.6 mM cysteamine, 0.00...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 1A2(Human)
Shanghai Meiyue Biotech Development Co.

US Patent
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 5.00E+4nMAssay Description:The CYP enzyme probe substrates used in the experiment were: Phenacetin (1A2), Bupropion (2B6), Amodiaquine (2C8), Mephenytoin (2C19), Diclofenac (2C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 2C9(Human)
Shanghai Meiyue Biotech Development Co.

US Patent
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 4.56E+4nMAssay Description:The CYP enzyme probe substrates used in the experiment were: Phenacetin (1A2), Bupropion (2B6), Amodiaquine (2C8), Mephenytoin (2C19), Diclofenac (2C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 2C19(Human)
Shanghai Meiyue Biotech Development Co.

US Patent
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 5.00E+4nMAssay Description:The CYP enzyme probe substrates used in the experiment were: Phenacetin (1A2), Bupropion (2B6), Amodiaquine (2C8), Mephenytoin (2C19), Diclofenac (2C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetCytochrome P450 2D6(Human)
Shanghai Meiyue Biotech Development Co.

US Patent
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 5.00E+4nMAssay Description:The CYP enzyme probe substrates used in the experiment were: Phenacetin (1A2), Bupropion (2B6), Amodiaquine (2C8), Mephenytoin (2C19), Diclofenac (2C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Shanghai Meiyue Biotech Development Co.

US Patent
LigandPNGBDBM668457(US20240124479, Compound 41-P2)
Affinity DataIC50: 5.00E+4nMAssay Description:The CYP enzyme probe substrates used in the experiment were: Phenacetin (1A2), Bupropion (2B6), Amodiaquine (2C8), Mephenytoin (2C19), Diclofenac (2C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent