BDBM668034 (R)-N-(2-(6,6-Dimethyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)-3H-imidazo[4,5-b]pyridin-6-yl)-N-ethyl-2-(tetrahydro-2H-pyran-4-yl)ProPenamide::US20240124439, Example 18

SMILES CCN(C(=O)[C@H](C)C1CCOCC1)c1cnc2[nH]c(nc2c1)-c1n[nH]c2CC(C)(C)CCc12

InChI Key InChIKey=HPTDVEAEHSVIQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668034   

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandPNGBDBM668034(US20240124439, Example 18 | (R)-N-(2-(6,6-Dimethyl...)
Affinity DataIC50: 28nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent