BDBM668022 N-Methyl-N-(2-((4aS,5aR)-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f]indazol-3-yl)-1H-imidazo[4,5-b]pyridin-6-yl)-2-(1H-pyrazol-1-yl)acetamide::US20240124439, Example 6

SMILES CN(C(=O)Cn1cccn1)c1cnc2nc([nH]c2c1)-c1n[nH]c2C[C@@]3(C)C[C@H]3Cc12

InChI Key InChIKey=WZQZYUMZEJYWSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668022   

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

US Patent
LigandPNGBDBM668022(US20240124439, Example 6 | N-Methyl-N-(2-((4aS,5aR...)
Affinity DataIC50: 26nMAssay Description:1.0 M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was st...More data for this Ligand-Target Pair
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Date in BDB:
7/9/2024
Entry Details
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