BDBM667809 US11958865, Example 5

SMILES CCc1c2Nc3ncc4c(Cl)nn(CCCOc2nn1-c1cccnc1OC)c4n3

InChI Key InChIKey=BDXRPYNNLQZBNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 667809   

Targetlrrk2 wt adpglo(Human)
H. Lundbeck

US Patent
LigandPNGBDBM667809(US11958865, Example 5)
Affinity DataIC50: 0.410nMAssay Description:In the assay, 0.5 nM LRRK2 WT kinase in kinase reaction buffer was incubated with the test compound (typically at 0 to 2 μM) for 30 minutes befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM667809(US11958865, Example 5)
Affinity DataIC50: 1.40nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase in kinase reaction buffer was incubated with the test compound (typically at 0 to 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

Targetlrrk2 wt adpglo(Human)
H. Lundbeck

US Patent
LigandPNGBDBM667809(US11958865, Example 5)
Affinity DataIC50: 4nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase in kinase reaction buffer was incubated with the test compound (typically at 0 to 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent