BDBM667758 N-(5-hydroxy-6-methyl- 1,2,3,4- tetrahydronaphthalen-1-yl)- 2-oxo-6-(trifluoromethyl)- 1,2-dihydropyridine-3- carboxamide::US11957687, Compound 231

SMILES Cc1ccc2C(CCCc2c1O)NC(=O)c1ccc([nH]c1=O)C(F)(F)F

InChI Key InChIKey=AXWKGCNUJJFNBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667758   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667758(N-(5-hydroxy-6-methyl- 1,2,3,4- tetrahydronaphthal...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2024
Entry Details
US Patent