BDBM667631 N-(2-ethyl-6- methylthiochroman-4-yl)-2- oxo-6-(trifluoromethyl)-1,2- dihydropyridine-3- carboxamide::US11957687, Compound 383

SMILES CCC1CC(NC(=O)c2ccc([nH]c2=O)C(F)(F)F)c2ccc(C)cc2S1

InChI Key InChIKey=QABLLIJCBYLNFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667631   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667631(N-(2-ethyl-6- methylthiochroman-4-yl)-2- oxo-6-(tr...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent