BDBM667583 N-(2,7-dimethoxy-9H- fluoren-9-yl)-2-oxo-6- (trifluoromethyl)-1,2- dihydropyridine-3- carboxamide::US11957687, Compound 415

SMILES COc1ccc-2c(c1)C(NC(=O)c1ccc([nH]c1=O)C(F)(F)F)c1cc(OC)ccc-21

InChI Key InChIKey=BYUDYRFLMJLHDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667583   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667583(N-(2,7-dimethoxy-9H- fluoren-9-yl)-2-oxo-6- (trifl...)
Affinity DataIC50: 50nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent