BDBM667493 5-(cyclohexylamino)-N-(3,6- dimethyl-10,10-dioxido-9H- thioxanthen-9-yl)-2-oxo-6- (trifluoromethyl)-1,2- dihydropyridine-3- carboxamide::US11957687, Compound 428

SMILES Cc1ccc2C(NC(=O)c3cc(NC4CCCCC4)c([nH]c3=O)C(F)(F)F)c3ccc(C)cc3S(=O)(=O)c2c1

InChI Key InChIKey=IOTPSNXSEXLEEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667493   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667493(5-(cyclohexylamino)-N-(3,6- dimethyl-10,10-dioxido...)
Affinity DataIC50: 20nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent