BDBM667490 5-(4-benzylpiperazin-1-yl)- N-(3,6-dimethyl-9H- xanthen-9-yl)-2-oxo-6- (trifluoromethyl)-1,2- dihydropyridine-3- carboxamide::US11957687, Compound 430

SMILES Cc1ccc2C(NC(=O)c3cc(N4CCN(Cc5ccccc5)CC4)c([nH]c3=O)C(F)(F)F)c3ccc(C)cc3Oc2c1

InChI Key InChIKey=GPKKXVWQLNUQTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667490   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667490(5-(4-benzylpiperazin-1-yl)- N-(3,6-dimethyl-9H- xa...)
Affinity DataIC50: 40nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
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Date in BDB:
7/3/2024
Entry Details
US Patent