BDBM667470 N-(3,6-dimethyl-10,10- dioxido-9H-thioxanthen-9- yl)-5-methyl-2-oxo-6- (trifluoromethyl)-1,2- dihydropyridine-3- carboxamide::US11957687, Compound 474

SMILES Cc1ccc2C(NC(=O)c3cc(C)c([nH]c3=O)C(F)(F)F)c3ccc(C)cc3S(=O)(=O)c2c1

InChI Key InChIKey=AGJGIMYLPGBSOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667470   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667470(N-(3,6-dimethyl-10,10- dioxido-9H-thioxanthen-9- y...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent