BDBM667468 N-(3,6-dimethyl-9H- xanthen-9-yl)-6,6'-dioxo-2- (trifluoromethyl)-1,1',6,6'- tetrahydro-[3,3'-bipyridine]- 5-carboxamide::US11957687, Compound 497

SMILES Cc1ccc2C(NC(=O)c3cc(-c4ccc(=O)[nH]c4)c([nH]c3=O)C(F)(F)F)c3ccc(C)cc3Oc2c1

InChI Key InChIKey=KINRZEBDJSSHDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667468   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Regeneron Pharmaceuticals

US Patent
LigandPNGBDBM667468(N-(3,6-dimethyl-9H- xanthen-9-yl)-6,6'-dioxo-2- (t...)
Affinity DataIC50: 30nMAssay Description:Compounds of the disclosure were screened for their ability to block HSD17B13 function using an enzymatic blocking assay. HSD17B13 activity was quant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent