BDBM667169 4-[7-(5-chloro-2-fluorophenyl)- 1H,2H,3H-pyrido[3,4- b][1,4]oxazin-1-yl]pyridine::US20240116947, Example 1

SMILES Fc1ccc(Cl)cc1-c1cc2N(CCOc2cn1)c1ccncc1

InChI Key InChIKey=NAWMEHQAUUGKKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667169   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667169(US20240116947, Example 1 | 4-[7-(5-chloro-2-fluoro...)
Affinity DataIC50: 7.5nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent