BDBM667132 N-{5-[6-(5-chloro-2-fluorophenyl)-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-8-yl]pyridin-3-yl}-3-(morpholin-4-yl)propenamide::US20240116948, Example 9

SMILES Fc1ccc(Cl)cc1-c1cc(-c2cncc(NC(=O)CCN3CCOCC3)c2)c2OCCNc2n1

InChI Key InChIKey=DMGMUTRNVLFJCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667132   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667132(US20240116948, Example 9 | N-{5-[6-(5-chloro-2-flu...)
Affinity DataIC50: 3nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
US Patent