BDBM667114 7-(5-chloro-2-fluorophenyl)-1-{2- [3-(4-methylpiperazin-1- yl)propanamido]pyridin-4-yl}- 1H,2H,3H-pyrido[3,4- b][1,4]oxazine-5-carboxylic acid::US20240116947, Example 44

SMILES CN1CCN(CCC(=O)Nc2cc(ccn2)N2CCOc3c2cc(nc3C(O)=O)-c2cc(Cl)ccc2F)CC1

InChI Key InChIKey=WHJXRHYVUNWKKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667114   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667114(US20240116947, Example 44 | 7-(5-chloro-2-fluoroph...)
Affinity DataIC50: 3nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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