BDBM667113 N-{4-[7-(5-chloro-2-fluorophenyl)- 1H,2H,3H-pyrido[3,4- b][1,4]oxazin-1-yl]pyridin-2-yl}-3- [(2- methanesulfonylethyl)(methyl) amino]propanamide::US20240116947, Example 27

SMILES CN(CCC(=O)Nc1cc(ccn1)N1CCOc2cnc(cc12)-c1cc(Cl)ccc1F)CCS(C)(=O)=O

InChI Key InChIKey=NQKBVVLNKFYZFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667113   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM667113(US20240116947, Example 27 | N-{4-[7-(5-chloro-2-fl...)
Affinity DataIC50: 3nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
6/29/2024
Entry Details
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